Blood clotting (VTE, DVT, PE)

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Information about blood clotting and its treatment

Blood clots can block blood flow and be life-threatening.

A venous thromboembolism (VTE) is a blood clot that forms in a vein while a deep vein thrombosis (DVT) is a blood clot, usually found in the arm or leg. A pulmonary embolism (PE) is when a clot breaks off and travels to the lungs.

Symptoms

Symptoms may include:

  • a fast or pounding heartbeat
  • chest pain, especially pain that gets worse when you take a deep breath
  • feeling short of breath or having trouble breathing
  • swelling, pain, or redness in an arm or leg.

Some people may not have any symptoms at all.

When to see a doctor

UrgencySymptoms
Emergency – get help immediatelyNew or severe chest pain, very low oxygen levels, feeling faint, dizzy or seriously unwell.
Urgent – needs prompt medical reviewSymptoms that could suggest a blood clot, such as leg swelling or pain, shortness of breath or chest pain.
Routine – planned follow-upOngoing check‑ups after a blood clot that was found incidentally (by chance) or is already being treated.

Common causes include:

  • cancer
  • hormonal therapy
  • obesity
  • pregnancy
  • surgery/immobility
  • thrombophilia.

Your doctor may arrange:

  • D‑dimer blood test that can help look for signs of a blood clot
  • ultrasound scan of the leg or arm to check for a clot in a vein if DVT suspected
  • CT pulmonary angiography, a special CT scan of the chest, to look for a blood clot in the lungs if PE suspected
  • thrombophilia blood testing, to see if you have an increased tendency to form blood clots. Usually only done in certain situations.

Treatment may include:

  • blood‑thinning medications (tablets or injections) that help stop the blood clot from growing and prevent new clots from forming
  • clot‑busting treatment medication used in serious or life‑threatening clots to quickly break down the clot
  • IVC filter, a small device placed in a vein to stop clots from travelling to the lungs, used only in certain situations
  • long‑term blood‑thinning treatment for higher‑risk patients, to reduce the risk of future clots.